notch pathway activator jagged1 Search Results


recombinant rat jagged1 fc  (R&D Systems)
94
R&D Systems recombinant rat jagged1 fc
Recombinant Rat Jagged1 Fc, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/recombinant rat jagged1 fc/product/R&D Systems
Average 94 stars, based on 1 article reviews
recombinant rat jagged1 fc - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier
gene exp pcna hs00427214 g1  (Thermo Fisher)
98
Thermo Fisher gene exp pcna hs00427214 g1
Gene Exp Pcna Hs00427214 G1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/gene exp pcna hs00427214 g1/product/Thermo Fisher
Average 98 stars, based on 1 article reviews
gene exp pcna hs00427214 g1 - by Bioz Stars, 2026-03
98/100 stars
  Buy from Supplier
jagged1 polyclonal antibody  (Santa Cruz Biotechnology)
96
Santa Cruz Biotechnology jagged1 polyclonal antibody
FIG. 8. Model describing the role of Notch signaling and <t>Jag1-Notch</t> interaction in zebrafish thyroid development. The thyroid primordium originates from the pharyngeal endoderm by 24 hpf. Our data indicate that Notch signaling originating from the endodermal layer itself or from the surrounding developing tissues plays a fundamental role in limiting the number of thyroidal differentiating precursors (double dotted arrow, 1, left side of the panel). The combined expression of nkx2.1a, pax2a, hhex, and pax8 is distinctive of the thyroid follicular cells. jag1b is mainly expressed starting from at 48 hpf; nevertheless, we can not completely exclude jag1b contribution in earlier phases of thyroid development (“jag1b?”), due to its spotted pattern of expression in the region of the thyroid primordium origin at 24 hpf; jag1a is mainly expressed at 72 hpf, in the most anterior portion of the first thyroid follicle. By 72 hpf, the thyroid tissue starts to elongate posteriorly and produce T4. Jag1-Notch signaling sustains these steps and the maintenance of thyroid cells (dotted black arrow, 2). jag1 loss-of- function conditions impair thyroid development and function (black arrow, 3). T, Thyroid; ch, ceratohyal; h, heart. Stages, upper part of the panel; 24 and 36 hpf, transversal views; from 48 to 120 hpf, ventral views.
Jagged1 Polyclonal Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/jagged1 polyclonal antibody/product/Santa Cruz Biotechnology
Average 96 stars, based on 1 article reviews
jagged1 polyclonal antibody - by Bioz Stars, 2026-03
96/100 stars
  Buy from Supplier
anti jag1  (Cell Signaling Technology Inc)
95
Cell Signaling Technology Inc anti jag1
FIG. 8. Model describing the role of Notch signaling and <t>Jag1-Notch</t> interaction in zebrafish thyroid development. The thyroid primordium originates from the pharyngeal endoderm by 24 hpf. Our data indicate that Notch signaling originating from the endodermal layer itself or from the surrounding developing tissues plays a fundamental role in limiting the number of thyroidal differentiating precursors (double dotted arrow, 1, left side of the panel). The combined expression of nkx2.1a, pax2a, hhex, and pax8 is distinctive of the thyroid follicular cells. jag1b is mainly expressed starting from at 48 hpf; nevertheless, we can not completely exclude jag1b contribution in earlier phases of thyroid development (“jag1b?”), due to its spotted pattern of expression in the region of the thyroid primordium origin at 24 hpf; jag1a is mainly expressed at 72 hpf, in the most anterior portion of the first thyroid follicle. By 72 hpf, the thyroid tissue starts to elongate posteriorly and produce T4. Jag1-Notch signaling sustains these steps and the maintenance of thyroid cells (dotted black arrow, 2). jag1 loss-of- function conditions impair thyroid development and function (black arrow, 3). T, Thyroid; ch, ceratohyal; h, heart. Stages, upper part of the panel; 24 and 36 hpf, transversal views; from 48 to 120 hpf, ventral views.
Anti Jag1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti jag1/product/Cell Signaling Technology Inc
Average 95 stars, based on 1 article reviews
anti jag1 - by Bioz Stars, 2026-03
95/100 stars
  Buy from Supplier
anti jagged 1 goat polyclonal igg  (R&D Systems)
93
R&D Systems anti jagged 1 goat polyclonal igg
FIG. 8. Model describing the role of Notch signaling and <t>Jag1-Notch</t> interaction in zebrafish thyroid development. The thyroid primordium originates from the pharyngeal endoderm by 24 hpf. Our data indicate that Notch signaling originating from the endodermal layer itself or from the surrounding developing tissues plays a fundamental role in limiting the number of thyroidal differentiating precursors (double dotted arrow, 1, left side of the panel). The combined expression of nkx2.1a, pax2a, hhex, and pax8 is distinctive of the thyroid follicular cells. jag1b is mainly expressed starting from at 48 hpf; nevertheless, we can not completely exclude jag1b contribution in earlier phases of thyroid development (“jag1b?”), due to its spotted pattern of expression in the region of the thyroid primordium origin at 24 hpf; jag1a is mainly expressed at 72 hpf, in the most anterior portion of the first thyroid follicle. By 72 hpf, the thyroid tissue starts to elongate posteriorly and produce T4. Jag1-Notch signaling sustains these steps and the maintenance of thyroid cells (dotted black arrow, 2). jag1 loss-of- function conditions impair thyroid development and function (black arrow, 3). T, Thyroid; ch, ceratohyal; h, heart. Stages, upper part of the panel; 24 and 36 hpf, transversal views; from 48 to 120 hpf, ventral views.
Anti Jagged 1 Goat Polyclonal Igg, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti jagged 1 goat polyclonal igg/product/R&D Systems
Average 93 stars, based on 1 article reviews
anti jagged 1 goat polyclonal igg - by Bioz Stars, 2026-03
93/100 stars
  Buy from Supplier
antibodies against jagged-1  (Santa Cruz Biotechnology)
90
Santa Cruz Biotechnology antibodies against jagged-1
FIG. 8. Model describing the role of Notch signaling and <t>Jag1-Notch</t> interaction in zebrafish thyroid development. The thyroid primordium originates from the pharyngeal endoderm by 24 hpf. Our data indicate that Notch signaling originating from the endodermal layer itself or from the surrounding developing tissues plays a fundamental role in limiting the number of thyroidal differentiating precursors (double dotted arrow, 1, left side of the panel). The combined expression of nkx2.1a, pax2a, hhex, and pax8 is distinctive of the thyroid follicular cells. jag1b is mainly expressed starting from at 48 hpf; nevertheless, we can not completely exclude jag1b contribution in earlier phases of thyroid development (“jag1b?”), due to its spotted pattern of expression in the region of the thyroid primordium origin at 24 hpf; jag1a is mainly expressed at 72 hpf, in the most anterior portion of the first thyroid follicle. By 72 hpf, the thyroid tissue starts to elongate posteriorly and produce T4. Jag1-Notch signaling sustains these steps and the maintenance of thyroid cells (dotted black arrow, 2). jag1 loss-of- function conditions impair thyroid development and function (black arrow, 3). T, Thyroid; ch, ceratohyal; h, heart. Stages, upper part of the panel; 24 and 36 hpf, transversal views; from 48 to 120 hpf, ventral views.
Antibodies Against Jagged 1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/antibodies against jagged-1/product/Santa Cruz Biotechnology
Average 90 stars, based on 1 article reviews
antibodies against jagged-1 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
monoclonal anti-cd31  (Novocastra)
90
Novocastra monoclonal anti-cd31
FIG. 8. Model describing the role of Notch signaling and <t>Jag1-Notch</t> interaction in zebrafish thyroid development. The thyroid primordium originates from the pharyngeal endoderm by 24 hpf. Our data indicate that Notch signaling originating from the endodermal layer itself or from the surrounding developing tissues plays a fundamental role in limiting the number of thyroidal differentiating precursors (double dotted arrow, 1, left side of the panel). The combined expression of nkx2.1a, pax2a, hhex, and pax8 is distinctive of the thyroid follicular cells. jag1b is mainly expressed starting from at 48 hpf; nevertheless, we can not completely exclude jag1b contribution in earlier phases of thyroid development (“jag1b?”), due to its spotted pattern of expression in the region of the thyroid primordium origin at 24 hpf; jag1a is mainly expressed at 72 hpf, in the most anterior portion of the first thyroid follicle. By 72 hpf, the thyroid tissue starts to elongate posteriorly and produce T4. Jag1-Notch signaling sustains these steps and the maintenance of thyroid cells (dotted black arrow, 2). jag1 loss-of- function conditions impair thyroid development and function (black arrow, 3). T, Thyroid; ch, ceratohyal; h, heart. Stages, upper part of the panel; 24 and 36 hpf, transversal views; from 48 to 120 hpf, ventral views.
Monoclonal Anti Cd31, supplied by Novocastra, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/monoclonal anti-cd31/product/Novocastra
Average 90 stars, based on 1 article reviews
monoclonal anti-cd31 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
jagged-1  (AnaSpec)
90
AnaSpec jagged-1
FIG. 8. Model describing the role of Notch signaling and <t>Jag1-Notch</t> interaction in zebrafish thyroid development. The thyroid primordium originates from the pharyngeal endoderm by 24 hpf. Our data indicate that Notch signaling originating from the endodermal layer itself or from the surrounding developing tissues plays a fundamental role in limiting the number of thyroidal differentiating precursors (double dotted arrow, 1, left side of the panel). The combined expression of nkx2.1a, pax2a, hhex, and pax8 is distinctive of the thyroid follicular cells. jag1b is mainly expressed starting from at 48 hpf; nevertheless, we can not completely exclude jag1b contribution in earlier phases of thyroid development (“jag1b?”), due to its spotted pattern of expression in the region of the thyroid primordium origin at 24 hpf; jag1a is mainly expressed at 72 hpf, in the most anterior portion of the first thyroid follicle. By 72 hpf, the thyroid tissue starts to elongate posteriorly and produce T4. Jag1-Notch signaling sustains these steps and the maintenance of thyroid cells (dotted black arrow, 2). jag1 loss-of- function conditions impair thyroid development and function (black arrow, 3). T, Thyroid; ch, ceratohyal; h, heart. Stages, upper part of the panel; 24 and 36 hpf, transversal views; from 48 to 120 hpf, ventral views.
Jagged 1, supplied by AnaSpec, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/jagged-1/product/AnaSpec
Average 90 stars, based on 1 article reviews
jagged-1 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
jagged 1  (Cell Signaling Technology Inc)
95
Cell Signaling Technology Inc jagged 1
FIG. 8. Model describing the role of Notch signaling and <t>Jag1-Notch</t> interaction in zebrafish thyroid development. The thyroid primordium originates from the pharyngeal endoderm by 24 hpf. Our data indicate that Notch signaling originating from the endodermal layer itself or from the surrounding developing tissues plays a fundamental role in limiting the number of thyroidal differentiating precursors (double dotted arrow, 1, left side of the panel). The combined expression of nkx2.1a, pax2a, hhex, and pax8 is distinctive of the thyroid follicular cells. jag1b is mainly expressed starting from at 48 hpf; nevertheless, we can not completely exclude jag1b contribution in earlier phases of thyroid development (“jag1b?”), due to its spotted pattern of expression in the region of the thyroid primordium origin at 24 hpf; jag1a is mainly expressed at 72 hpf, in the most anterior portion of the first thyroid follicle. By 72 hpf, the thyroid tissue starts to elongate posteriorly and produce T4. Jag1-Notch signaling sustains these steps and the maintenance of thyroid cells (dotted black arrow, 2). jag1 loss-of- function conditions impair thyroid development and function (black arrow, 3). T, Thyroid; ch, ceratohyal; h, heart. Stages, upper part of the panel; 24 and 36 hpf, transversal views; from 48 to 120 hpf, ventral views.
Jagged 1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/jagged 1/product/Cell Signaling Technology Inc
Average 95 stars, based on 1 article reviews
jagged 1 - by Bioz Stars, 2026-03
95/100 stars
  Buy from Supplier
recombinant human jagged 1 fc chimera protein, cf  (Bio-Techne corporation)
95
Bio-Techne corporation recombinant human jagged 1 fc chimera protein, cf
FIG. 8. Model describing the role of Notch signaling and <t>Jag1-Notch</t> interaction in zebrafish thyroid development. The thyroid primordium originates from the pharyngeal endoderm by 24 hpf. Our data indicate that Notch signaling originating from the endodermal layer itself or from the surrounding developing tissues plays a fundamental role in limiting the number of thyroidal differentiating precursors (double dotted arrow, 1, left side of the panel). The combined expression of nkx2.1a, pax2a, hhex, and pax8 is distinctive of the thyroid follicular cells. jag1b is mainly expressed starting from at 48 hpf; nevertheless, we can not completely exclude jag1b contribution in earlier phases of thyroid development (“jag1b?”), due to its spotted pattern of expression in the region of the thyroid primordium origin at 24 hpf; jag1a is mainly expressed at 72 hpf, in the most anterior portion of the first thyroid follicle. By 72 hpf, the thyroid tissue starts to elongate posteriorly and produce T4. Jag1-Notch signaling sustains these steps and the maintenance of thyroid cells (dotted black arrow, 2). jag1 loss-of- function conditions impair thyroid development and function (black arrow, 3). T, Thyroid; ch, ceratohyal; h, heart. Stages, upper part of the panel; 24 and 36 hpf, transversal views; from 48 to 120 hpf, ventral views.
Recombinant Human Jagged 1 Fc Chimera Protein, Cf, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/recombinant human jagged 1 fc chimera protein, cf/product/Bio-Techne corporation
Average 95 stars, based on 1 article reviews
recombinant human jagged 1 fc chimera protein, cf - by Bioz Stars, 2026-03
95/100 stars
  Buy from Supplier
jagged 1 recombinant protein antigen  (Bio-Techne corporation)
90
Bio-Techne corporation jagged 1 recombinant protein antigen
FIG. 8. Model describing the role of Notch signaling and <t>Jag1-Notch</t> interaction in zebrafish thyroid development. The thyroid primordium originates from the pharyngeal endoderm by 24 hpf. Our data indicate that Notch signaling originating from the endodermal layer itself or from the surrounding developing tissues plays a fundamental role in limiting the number of thyroidal differentiating precursors (double dotted arrow, 1, left side of the panel). The combined expression of nkx2.1a, pax2a, hhex, and pax8 is distinctive of the thyroid follicular cells. jag1b is mainly expressed starting from at 48 hpf; nevertheless, we can not completely exclude jag1b contribution in earlier phases of thyroid development (“jag1b?”), due to its spotted pattern of expression in the region of the thyroid primordium origin at 24 hpf; jag1a is mainly expressed at 72 hpf, in the most anterior portion of the first thyroid follicle. By 72 hpf, the thyroid tissue starts to elongate posteriorly and produce T4. Jag1-Notch signaling sustains these steps and the maintenance of thyroid cells (dotted black arrow, 2). jag1 loss-of- function conditions impair thyroid development and function (black arrow, 3). T, Thyroid; ch, ceratohyal; h, heart. Stages, upper part of the panel; 24 and 36 hpf, transversal views; from 48 to 120 hpf, ventral views.
Jagged 1 Recombinant Protein Antigen, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/jagged 1 recombinant protein antigen/product/Bio-Techne corporation
Average 90 stars, based on 1 article reviews
jagged 1 recombinant protein antigen - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
human jagged 1 antibody  (Bio-Techne corporation)
94
Bio-Techne corporation human jagged 1 antibody
FIG. 8. Model describing the role of Notch signaling and <t>Jag1-Notch</t> interaction in zebrafish thyroid development. The thyroid primordium originates from the pharyngeal endoderm by 24 hpf. Our data indicate that Notch signaling originating from the endodermal layer itself or from the surrounding developing tissues plays a fundamental role in limiting the number of thyroidal differentiating precursors (double dotted arrow, 1, left side of the panel). The combined expression of nkx2.1a, pax2a, hhex, and pax8 is distinctive of the thyroid follicular cells. jag1b is mainly expressed starting from at 48 hpf; nevertheless, we can not completely exclude jag1b contribution in earlier phases of thyroid development (“jag1b?”), due to its spotted pattern of expression in the region of the thyroid primordium origin at 24 hpf; jag1a is mainly expressed at 72 hpf, in the most anterior portion of the first thyroid follicle. By 72 hpf, the thyroid tissue starts to elongate posteriorly and produce T4. Jag1-Notch signaling sustains these steps and the maintenance of thyroid cells (dotted black arrow, 2). jag1 loss-of- function conditions impair thyroid development and function (black arrow, 3). T, Thyroid; ch, ceratohyal; h, heart. Stages, upper part of the panel; 24 and 36 hpf, transversal views; from 48 to 120 hpf, ventral views.
Human Jagged 1 Antibody, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human jagged 1 antibody/product/Bio-Techne corporation
Average 94 stars, based on 1 article reviews
human jagged 1 antibody - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier

Image Search Results


FIG. 8. Model describing the role of Notch signaling and Jag1-Notch interaction in zebrafish thyroid development. The thyroid primordium originates from the pharyngeal endoderm by 24 hpf. Our data indicate that Notch signaling originating from the endodermal layer itself or from the surrounding developing tissues plays a fundamental role in limiting the number of thyroidal differentiating precursors (double dotted arrow, 1, left side of the panel). The combined expression of nkx2.1a, pax2a, hhex, and pax8 is distinctive of the thyroid follicular cells. jag1b is mainly expressed starting from at 48 hpf; nevertheless, we can not completely exclude jag1b contribution in earlier phases of thyroid development (“jag1b?”), due to its spotted pattern of expression in the region of the thyroid primordium origin at 24 hpf; jag1a is mainly expressed at 72 hpf, in the most anterior portion of the first thyroid follicle. By 72 hpf, the thyroid tissue starts to elongate posteriorly and produce T4. Jag1-Notch signaling sustains these steps and the maintenance of thyroid cells (dotted black arrow, 2). jag1 loss-of- function conditions impair thyroid development and function (black arrow, 3). T, Thyroid; ch, ceratohyal; h, heart. Stages, upper part of the panel; 24 and 36 hpf, transversal views; from 48 to 120 hpf, ventral views.

Journal: Endocrinology

Article Title: Disruptions of global and JAGGED1-mediated notch signaling affect thyroid morphogenesis in the zebrafish.

doi: 10.1210/en.2011-1888

Figure Lengend Snippet: FIG. 8. Model describing the role of Notch signaling and Jag1-Notch interaction in zebrafish thyroid development. The thyroid primordium originates from the pharyngeal endoderm by 24 hpf. Our data indicate that Notch signaling originating from the endodermal layer itself or from the surrounding developing tissues plays a fundamental role in limiting the number of thyroidal differentiating precursors (double dotted arrow, 1, left side of the panel). The combined expression of nkx2.1a, pax2a, hhex, and pax8 is distinctive of the thyroid follicular cells. jag1b is mainly expressed starting from at 48 hpf; nevertheless, we can not completely exclude jag1b contribution in earlier phases of thyroid development (“jag1b?”), due to its spotted pattern of expression in the region of the thyroid primordium origin at 24 hpf; jag1a is mainly expressed at 72 hpf, in the most anterior portion of the first thyroid follicle. By 72 hpf, the thyroid tissue starts to elongate posteriorly and produce T4. Jag1-Notch signaling sustains these steps and the maintenance of thyroid cells (dotted black arrow, 2). jag1 loss-of- function conditions impair thyroid development and function (black arrow, 3). T, Thyroid; ch, ceratohyal; h, heart. Stages, upper part of the panel; 24 and 36 hpf, transversal views; from 48 to 120 hpf, ventral views.

Article Snippet: For Jag1 immunofluorescence on mouse thyroid tissue, sections (5 m) cut from OCT-embedded tissue blocks were blocked with 1% BSA/2% donkey serum and immunostained overnight at 4 C with Jagged1 polyclonal antibody (1:100, H-114; Santa Cruz Biotechnology, Inc., Santa Cruz, CA).

Techniques: Expressing